Okemoto-Nakamura Y, Tanida I, Yamaji T, Hanada K, Hagiwara K. A PRNP-disrupted human neuroblastoma cell line and its stable transformants expressing prion protein variants. BPB Reports, 2 (5): 73-79 (2019). FREE Access
Hagiwara K, Sato Y, Yamakawa Y, Hara H, Tobiume M, Okemoto-Nakamura Y, Sata T, Horiuchi M, Shibata H, and Ono F. Tracking and clarifying differential traits of classical- and atypical L-type bovine spongiform encephalopathy prions after transmission from cattle to cynomolgus monkeys. PLoS One, 14(5): e0216807 (2019). FREE Access
2017年
Hagiwara K, Iwamaru Y, Tabeta N, Yokoyama T, Tobiume M. Evaluation of rapid post-mortem test kits for bovine spongiform encephalopathy (BSE) screening in Japan: Their analytical sensitivity to atypical BSE prions. Prion, 11: 113-127 (2017). FREE Access
2013年
Matsuura Y, Ishikawa Y, Somerville RA, Yokoyama T, Hagiwara K, Yamakawa Y, Sata T, Kitamoto T, Mohri S. A rapid bioassay for classical and L-type bovine spongiform encephalopathies. Open J Vet Med, 3 (2013) doi 10.4236/ojvm.2013.31013. FREE Access
Hagiwara K, Hara H, Hanada K. Species-barrier phenomenon in prion transmissibility from a viewpoint of protein science. (Review) J Biochem, 153: 139-145 (2013). FREE Access
2012年
Hara H, Okemoto-Nakamura Y, Shinkai-Ouchi F, Hanada K, Yamakawa Y, Hagiwara K. Mouse prion protein (PrP) segment 100 to 104 regulates conversion of PrPC to PrPSc in prion-infected neuroblastoma cells. J Virol, 86: 5626-5636 (2012). FREE Access
2011年
Ono F, Tase N, Kurosawa A, Hiyaoka A, Ohyama A, Tezuka Y, Wada N, Sato Y, Tobiume M, Hagiwara K, Yamakawa Y, Terao K, Sata T. Atypical L-type bovine spongiform encephalopathy (L-BSE) transmission to cynomolgus macaques, a non-human primate. Jpn J Infect Dis, 64: 81-84 (2011). FREE Access
Ono F, Terao K, Tase N, Hiyaoka A, Ohyama A, Tezuka Y, Wada N, Kurosawa A, Sato Y, Tobiume M, Hagiwara K, Yamakawa Y, Sata T. Experimental transmission of bovine spongiform encephalopathy (BSE) to cynomolgus macaques, a non-human primate. Jpn J Infect Dis, 64: 50-54 (2011). FREE Access
2010年
Shinkai-Ouchi F, Yamakawa Y, Hara H, Tobiume M, Nishijima M, Hanada K, Hagiwara K. Identification and structural analysis of C-terminally truncated collapsin response mediator protein-2 in a murine model of prion diseases. Proteome Sci. 8: 53 (2010). FREE Access
Tanaka M, Hara H, Nishina H, Hanada K, Hagiwara K, Maehama T. An improved method for cell-to-cell transmission of infectious prion. Biochem Biophys Res Commun, 397: 505-508 (2010).
Iwamaru Y, Imamura M, Matsuura Y, Masujin K, Shimizu Y, Shu Y, Kurachi M, Kasai K, Murayama Y, Fukuda S, Onoe S, Hagiwara K, Yamakawa Y, Sata T, Mohri S, Okada H, Yokoyama T. Accumulation of L-type bovine prions in peripheral nerve tissues. Emerg Infect Dis, 16: 1151-1154 (2010). FREE Access
Sato Y, Shimonohara,N, Hanaki K, Goto M, Yamakawa Y, Horiuchi M, Takahashi H, Sata T, Nakajima N. ImmunoAT method: An initial assessment for the detection of abnormal isoforms of prion protein in formalin-fixed and paraffin-embedded tissues. J Virol Methods, 165: 261-267 (2010).
2009年
Fukuda S, Iwamaru Y, Imamura M, Masujin K, Shimizu Y, Matsuura Y, Shu Y, Kurachi M, Kasai K, Murayama Y, Onoe S, Hagiwara K, Sata T, Mohri S, Yokoyama T, Okada H. Intraspecies transmission of L-type-like bovine spongiform encephalopathy detected in Japan. Microbiol Immunol, 53: 704-707 (2009).
Sato H, Kusumoto-Matsuo R, Ishii Y, Mori S, Nakahara T, Shinkai-Ouchi F, Kawana K, Fujii T, Taketani Y, Kanda T, Kukimoto I. Identification of nucleolin as a protein that binds to human papillomavirus type 16 DNA. Biochem Biophys Res Commun,387: 525-530 (2009).
Ogawa M, Shinkai-Ouchi F, Matsutani M, Uchiyama T, Hagiwara K, Hanada K, Kurane I, Kishimoto T. Shotgun proteomics of Orientia tsutsugamushi. Clin Microbiol Infect,15: 239-240 (2009).
Hara H, Aizaki H, Matsuda M, Shinkai-Ouchi F, Inoue Y, Murakami K, Shoji I, Kawakami H, Matsuura Y, Lai M M, Miyamura T, Wakita T, Suzuki T. Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein. J Virol, 83: 5137-5147 (2009).
2008年
Okemoto-Nakamura Y, Yamakawa Y, Hanada K, Tanaka K, Miura M, Tanida I, Nishijima M, Hagiwara K. A synthetic fibril peptide promotes clearance of scrapie prion protein by lysosomal degradation. Microbiol Immunol, 52: 357-365 (2008).
Masujin K, Shu Y, Yamakawa Y, Hagiwara K, Sata T, Matsuura Y, Iwamaru Y, Imamura M, Okada H, Mohri S, Yokoyama T. Biological and biochemical characterization of L-type-like bovine spongiform encephalopathy (BSE) detected in Japanese black beef cattle. Prion, 2: 123-128 (2008).
Yamamoto T, Ushiki Y, Hara S, Hall W W, Tsukagoshi-Nagai H, Yokoyama T, Tagawa Y, Sata T, Yamakawa Y, Kinoshita N, Tamura F, Hattori S, Irie S. An advantageous method utilizing new homogenizing device BioMasher and a senstitive ELISA to detect bovine spongiform encephalopathy accurately in brain tissue. J Virol Methods, 149: 316-325 (2008).
Katadae M, Hagiwara K, Wada A, Ito M, Umeda M, Casey P J, Fukada Y. Interacting targets of the farnesyl of transducin γ-subunit. Biochemistry, 47: 8424-8433 (2008).
2007年
Hagiwara K, Yamakawa Y, Sato Y, Nakamura Y, Tobiume M, Shinagawa M, Sata T. Accumulation of mono–glycosylated form–rich, plaque–forming PrPSc in the second atypical bovine encephalopathy case in Japan. Jpn J Infect Dis, 60: 305–308 (2007). FREE Access
Hagiwara K, Nakamura Y, Nishijima M, Yamakawa Y. Prevention of prion propagation by dehydrocholesterol reductase inhibitors in cultured cells and a therapeutic trial in mice. Biol Pharm Bull, 30: 835-838 (2007). FREE Access
Ishii Y, Kondo K, Matsumoto T, Tanaka K, Shinkai-Ouchi F, Hagiwara K, Kanda T. Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L1. Virol J, 4: 110 (2007). FREE Access
Yokoyama T, Masujin K, Yamakawa Y, Sata T, Murayama Y, Shu Y, Okada H, Mohri S, Shinagawa M. Experimental transmission of two young and one suspended bovine spongiform encephalopathy (BSE) cases to bovinized transgenic mice. Jpn J Infect Dis, 60: 317-320 (2007). FREE Access
Furuoka H, Yabuzoe A, Horiuchi M, Tagawa Y, Yokoyama T, Yamakawa Y, Shinagawa M, Sata T. Species-specificity of a panel of prion protein antibodies for the immunohistochemical study of animal and human prion diseases. J Comp Path, 136: 9-17 (2007).
2006年
Iwata N, Sato Y, Higuchi Y, Nohtomi K, Nagata N, Hasegawa H, Tobiume M, Nakamura Y, Hagiwara K, Furuoka H, Horiuchi M, Yamakawa Y, Sata T. Distribution of PrPSc in the cattle with bovine spongiform encephalopathy slaughtered at abattoirs in Japan. Jpn J Infect Dis, 59: 100-107 (2006). FREE Access
Furuya K, Kawahara N, Yamakawa Y, Kishida H, Hachiya N S, Nishijima M, Kirino T, Kaneko K. Intracerebroventricular delivery of dominant negative prion protein in a mouse model of iatrogenic Creutzfeldt-Jakob disease after dura graft transplantation. Neurosci Lett, 402: 222–226 (2006).
Yanagisawa Y, Sato Y, Asahi-Ozaki Y, Ito E, Honma R, Imai J, Kanno T, Kano M, Akiyama H, Sata T, Shinkai-Ouchi F, Yamakawa Y, Watanabe S, Katano H. Effusion and solid lymphomas have distinctive gene and protein expression profiles in an animal model of primary effusion lymphoma. J Pathol, 209: 464-73 (2006).
Sato S, Fukasawa M, Yamakawa Y, Natsume T, Suzuki T, Shoji I, Aizaki H, Miyamura T, Nishijima M. Proteomic profiling of lipid droplet proteins in hepatoma cell lines expressing hepatitis C virus core protein. J Biochem, 139: 921–930 (2006).