This Department, consisting of four sections, the General Affairs Division, the Personnel Division, the Accounting Division, the Business Operation Division, the Business Administration Division, and the Facility Management Division is in charge of general institutional affairs as a supporting section for research promotion to help efficiently carry out assay and research activities.

In addition, the department has the editorial office of Japanese Journal of Infectious Diseases (https://www.niid.go.jp/niid/en/jjid.html) published by this institute and the library which is to collect and preserve books in the fields of virology, bacteriology, parasitology, pathology, immunology, epidemiology, etc.