The Department of Fungal Infection is responsible for conducting surveillance studies, providing reference laboratory service for fungal infections, quality management of anti-infectious agents, diagnostic testing, epidemiological investiga-tion and monitoring drug-resistant fungi in cooperation with local health institutions. Our research focuses on identifying virulence factors important in fungal infection, investigating mechanisms of host defense regulation and developing novel anti-infectious agents, diagnostic methods and vaccines.

LABORATORY OF CLINICAL MYCOLOGY
  • Researches for candidiasis and mycoses caused by highly virulent fungi.
  • Diagnostic testing and reference laboratory service for fungal infections.
  • Research on fungal virulence and its application to treatments.
  • Investigation on the mechanism of action of anti-fungal agents and resistance.
  • International co-operation for training and research support associated with mycoses.
LABORATORY OF FILAMENTOUS MYCOSES
  • Researches for aspergillosis and mucormycosis.
  • Investigation of activity of anti-fungal agents and drug-drug interaction.
  • Investigation of cell growth and host-pathogen interaction of filamentous fungi.
LABORATORY OF HOST DEFENSE
  • Researches for cryptococcosis and skin mycoses.
  • Investigation of defense mechanisms against fungal infection and development of anti-fungal prevention/treatments.
  • Investigation of induction and regulatory mechanisms of infectious immunity.
LABORATORY OF EMERGING INFECTIONS AND ANTIMICROBIALS
  • Researches for rare invasive mycoses and anti-infective agents.
  • Bioinformatic analysis on mechanisms of drug resistance.
  • Identification of secondary metabolites from fungi and actinomycetes, and its application for developing anti-infectious treatments.
  • Administrative spot examination for generic antimicrobial agents.

Copyright 1998 National Institute of Infectious Diseases, Japan