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ここでは、学術雑誌に掲載された感染研の研究者の論文や報道等のあった研究成果の要約を公開することで、感染研が行っている研究業務を紹介していきます。
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Pathogen Genomics Center, National Institute of Infectious Diseases.
Analysis of whole genome sequences provides information that is useful for tracing back infection using genome-wide SNVs among clusters. During the primary wave, local public health centers were able to identify likely COVID-19 patients and their close contacts within location-specific clusters by conducting active epidemiological surveillance using the keywords “Wuhan, Hubei, and China.” Just as the situation had begun to improve around mid-March, a large number of new COVID-19 patients were diagnosed, many of with unclear infection routes. Tracing the infection routes was difficult because some Japanese cases had no recent history of travel to China or any country outside Japan. The SARS-CoV-2 haplotype network analysis suggested that the second wave of COVID-19 cases could have been imported via the returnees from EU, North America, or other countries.
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October 5, 2016
This international collaborative project by VLP Therapeutics, Nagasaki University and National Institute of Infectious diseases (NIID), supported by Global Health Innovation Technology [GHIT] Fund, is a pre-clinical study to investigate safety and immunogenicity of a virus-like particle (VLP)-based vaccine against Dengue virus infection.
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Tetsuro Matano, AIDS Research Center, April 2, 2013
The New York-based International AIDS Vaccine Initiative (IAVI) and the Japan-based biotech DNAVEC Corporation announced the start of a Phase I clinical trial of an HIV vaccine candidate using Sendai virus (SeV) vector at three locations including England and Rwanda. The SeV vector AIDS vaccine system has been developed by AIDS Research Center, National Institute of Infectious Diseases and Institute of Medical Science, University of Tokyo.
Press release from IAVI on April 1, 2013
http://www.iavi.org/Information-Center/Press-Releases/Pages/IAVI-AND-PARTNERS-INITIATE-PHASE-I-TRIAL-OF-A-NOVEL-AIDS-VACCINE-REGIMEN.aspx
Information on this project in IAVI Web
http://www.iavi.org/Information-Center/Publications/Pages/AIDS-Vaccine-Development-in-Japan.aspx