The aim of the Protein Kinase Database Project (PKDBP) project is to
develope a
resource that provides the user with a
compendium of current information on protein kinases, derived from a broad spectrum
of information sources and formats. Information access is designed around a
user-friendly, graphical interface that allows the user to browse or search
transparently (that is, providing access to information from various electronic
resources; web sites, gopher holes, e-newsgroups, ftp archives, databases,
search engines, etc., and information formats; audio, graphical, textual,
numerical).
The ultimate goal of this project is to develope a model scientific information
system that can be applied to other sets of biological data. A natural extension
of our work on protein kinases would be the creation of another
information system focused on protein phoshatases. Ideally we hope the model
we create here can be extended to other protein groups and other forms of
biological data.
Functions of the resource are to provide:
- an alternative mode for "publication" of research results and
a mechanism whereby researchers can receive recognition for their
contributions,
- a user-friendly mechanism (web browser) to access a variety of information
regardlesss of that information's location and electronic format,
- a mechanism to integrate various local and remote information
resources (textual, graphical, numerical)
- creation of a repository of information that is not available via current
public databases.
- Dr. Helen M. Berman, PhD
- Department of Chemistry
- Wright Chemistry Building, Room 113
- Rutgers, The State University of New Jersey
- Piscataway, New Jersey 08854 USA
- Dr. Jack E. Dixon, PhD
- Department of Biological Chemistry
- Medical Science I M5416
- 1301 Catherine Road
- The University of Michigan Medical School
- Ann Arbor, Michigan 48109-0606 USA
- Dr. Heidi Hamm, PhD
- Department of Molecular Pharmacology & Biology Chemistry
- 330 East Chicago Avenue
- Northwestern University Medical School
- Chicago, Illinois 60611-3008 USA
- Dr. Tony Hunter, PhD
- The Salk Institute for Biological Sciences
- 10010 North Torrey Pines Road
- P.O. Box 85800
- San Diego, California 92186-5800 USA
- Dr. Louise N. Johnson, PhD
- Department of Biochemistry
- Laboratory of Molecular Biophysics
- The Rex Richards Building
- South Parks Road
- University of Oxford
- Oxford OX1 3QU England
- Dr. John Kuriyan, PhD
- Howard Hughes Medical Institute
- Laboratories for Molecular Biophysics
- 1230 York Avenue
- The Rockefeller University
- New York, New York 10021
- Dr. Tony Pawson, PhD
- Samuel Lunenfeld Research Institute
- 600 University Avenue
- Mount Sinai Hospital
- Toronto, Ontario
- Canada M5G 1X5
- Dr. Susan Taylor, PhD
- Department of Chemistry & Biochemistry
- Cellular and Molecular Medicine-West, Room 126
- School of Medicine
- University of California at San Diego
- 9500 Gilman Drive
- La Jolla, California 92093-0654 USA
- Dr. Alfred Wittinghofer, PhD
- Abteilung Struckturelle Biologie
- Max Planck-Institut fur Molekulare Physiologie
- Rheinlanddamm 201
- 44139 Dortmund Germany
- National Science Foundation (USA) through Cooperative Agreement DASC-8902825.
- A Portable Client server Management System for the Comparative Analysis of Proteins supported by the National Science Foundation (USA).
- Christopher M. Smith, Michael Gribskov, Ilya N. Shindyalov, Susan S. Taylor, Lynn Ten Eyck, Stella Veretnik and
Philip E. Bourne. The Protein Kinase Resource , Trends in Biochemical Sciences, November 1997 ( in press )
Information and material are added to the The PROTEIN KINASE RESOURCE (http://www.sdsc.edu/Kinases/) on an as avaialable basis. Major additions and/or changes are noted in the "What's New" page. All hypertext links are validated once per month, which constitutes a version release for the following month. To contact the curators, please send an email to the Protein Kinase Resource Development Group,
or surface mail to:
Protein Kinase Resource Development Group
c/o Phil Bourne
San Diego Supercomputer Center
P.O. Box 85608
San Diego, CA 92186-5608
(619) 534-5113 (FAX)
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Last modified Tuesday, 23 September 1997 by Christopher Smith