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Research Activity

Some recent studies conducted in this division are as follows:

1) The effect of Japanese traditional diet and Americanized recent diet on fatty acid composition of erythrocyte membrane and plasma in young adult women. The relation of the frequency of food intake with plasma DHA content is also studying.


(Figure 1 Polyunsaturated fatty acids n-3 series in breast milk from Nigerian and Japanese women.)

2) The natalty in Japan is getting lower in recent years. We are working on the relation of the lifestyles with the fertility of young adult women. We also compare the lifestyles of pregnant women with the women planning for pregnancy.


(Figure 2 A thermographic pattern of the body surface of healthy menstrating woman.)

3) The analysis of the genomic structure of rat cysteine dioxygenase, a key enzyme of taurine biosynthesis. We also carry out the research on development and the clinical application to the gene diagnosis of taurine disorder and neurological diseases.


(Figure 3 Cysteine dioxygenase pathway and restriction map of the cDNA.)

4) The effect of dietary protein on cellular immune response on c57BL/6 young mices.

5) The development of novel and ultrasensitive enzyme immunoassay for general health care. We also carry out the thermographic analysis as a method of noninvasive diagnosis.

6) The analysis of liver-type arginase in serum as a sensitive marker for hepatic lesions.

7) The analysis of myeloperoxidase gene expression and the clinical application to the gene diagnosis for leukemia. We are working on the studies of the protein complex formation of the human myeloperoxidase on the immunological function.


khirota@nih.go.jp