<HTML>  

<HEAD>

  <TITLE>Hoshina et al., Cytomegalovirus-Associated Protein-Losing Enteropathy</TITLE>

</HEAD>

<BODY>


<P>Jpn. J. Infect. Dis., 62 (3), 236-238, 2009</P>


<P><FONT COLOR="#990099">To see a printable version of the article

in the Adobe file format, click this [</FONT><A HREF="236.pdf">PDF</A><FONT

 COLOR="#990099">] link.</FONT></P>


<P>Short Communication</P>


<P><B><FONT SIZE="+2">Cytomegalovirus-Associated Protein-Losing Enteropathy Resulting from Lymphangiectasia in 

an Immunocompetent Child</FONT></B></P>


<P><B>Takayuki Hoshina*, Koichi Kusuhara, Mitsumasa Saito, Takuya Hara, Shuji Matsuura<FONT SIZE="-1"><sup>1</sup></Font>, 

Takashi Yao<FONT SIZE="-1"><sup>2</sup></Font>, Tomonobu Aoki<FONT SIZE="-1"><sup>3</sup></Font>, and Toshiro Hara</B></P>


<P>Department of Pediatrics, <FONT SIZE="-1"><sup>1</sup></Font>Department of Clinical Radiology, and 

<FONT SIZE="-1"><sup>2</sup></Font>Department of Anatomic Pathology, Graduate School of Medical Sciences, 

Kyushu University, Fukuoka 812-8582, and 

<FONT SIZE="-1"><sup>3</sup></Font>Fukuoka Children's Hospital and Medical Centre for Infectious Diseases, 

Fukuoka 810-0063, Japan</P>


<P>(Received January 20, 2009. Accepted April 14, 2009)</P>


<P><HR ALIGN=LEFT></P>


<P>*Corresponding author: Mailing address: Department of Pediatrics, Graduate School of Medical Sciences, 

Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. Tel: +81-92-642-5421, 

Fax: +81-92-642-5435, E-mail: hoshina@pediatr.med.kyushu-u.ac.jp</P>


<P><HR ALIGN=LEFT></P>


<P><B>SUMMARY</B>: An immunocompetent 8-year-old boy with cytomegalovirus (CMV)-associated transient 

protein-losing enteropathy (PLE) is described. Colonoscopic examination revealed lymphoid hyperplasia of the 

terminal ileum. Histological examination of the biopsied specimens showed marked dilation of the lymphatic vessels. 

Primary CMV infection was demonstrated by serological test and polymerase chain reaction. The child had complete 

resolution of the disease without antiviral treatment. The present case suggests the etiologic role of CMV 

infection in PLE resulting from intestinal lymphangiectasia in childhood.</P>


<P><HR ALIGN=LEFT></P>


<P><A HREF="http://www.nih.go.jp/JJID/jjid.html">Go to JJID Homepage</A></P>


<P><A HREF="62-3.html">Go to JJID 62 (3) Contents</A>


</BODY>

</HTML>

�